About Genomics

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Screen Shot 2015-12-18 at 9.08.27 PM.pngBeginning with the Human Genome Project in 1984, the field of genomics has involved identifying and mapping the genes of the human genome, and categorizing those genes in regards to their physical and functional relationships.  The successful results of this project have triggered a tremendous amount of research aimed at understanding the most complex biological systems in the human body.  

Genomics Today

The rapid advances in technology, as well as the vast amount of data collected in genomic research, has greatly reduced the costs of genetic sequencing, providing for further expansion in other spaces, including:

  • Academic Researchers - further discovery of new genes and their association with specific health conditions
  • Clinical Providers - using biomarker tests as a reliable tool for recognizing the potential diseases and improve diagnoses.
  • Consumers - improving life choices based on knowledge about their genetic tendencies.


Screen Shot 2015-12-18 at 9.12.34 PM.pngHow Can Quibble Genomics Help?

While there are several sources for general and technical information regarding genomics, applying that information in a useful manner to a specific person is very difficult.  Quibble Genomics is committed to educate and inform both consumers and professionals.  We strive to present the information in a useful, convenient, and reliable manner, so that better decisions can be made regarding one’s health. 

 

 

Other Resources

For more information regarding the field of genomics, browse any of the links below, or contact us and we’ll be happy to help.

PUBMED - PubMed is a service of the US National Library of Medicine® that: Provides free access to MEDLINE®, the NLM® database of indexed citations and abstracts to medical, nursing, dental, veterinary, health care, and preclinical sciences journal articles.

NCBI - The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health.

GTR - The Genetic Testing Registry (GTR®) provides a central location for voluntary submission of genetic test information by providers.

CLINVAR - ClinVar is a freely accessible, public archive of reports of the relationships among human variations and phenotypes, with supporting evidence.

SNPEDIA - SNPedia (pronounced "snipedia") is a wiki-based bioinformatics web site that serves as a database of single nucleotide polymorphisms (SNPs). Each article on a SNP provides a short description, links to scientific articles and personal genomics web sites, as well as microarray information about that SNP.

DBSNP - The Single Nucleotide Polymorphism Database (dbSNP) is a free public archive for genetic variation within and across different species developed and hosted by the National Center for Biotechnology Information (NCBI) in collaboration with the National Human Genome Research Institute (NHGRI).

Alignment-free - The emergence and need for the analysis of different types of data generated through biological research has given rise to the field of bioinformatics. The advent of next generation sequencing technologies has resulted in generation of voluminous sequencing data. The size of this sequence data poses challenges on alignment-based algorithms in their assembly, annotation and comparative studies. Thus, alignment-free sequence analysis approaches provide attractive alternatives over alignment-based approaches.

Precision medicine - Precision medicine (PM) is a medical model that proposes the customization of healthcare, with medical decisions, practices, and/or products being tailored to the individual patient.

Personalized medicine - Personalized medicine or PM is a medical model that proposes the customization of healthcare - with medical decisions, practices, and/or products being tailored to the individual patient.

Population health - Population health has been defined as "the health outcomes of a group of individuals, including the distribution of such outcomes within the group". It is an approach to health that aims to improve the health of an entire human population.

Quibble co-founder Dr. Rao's research

Public Workshop - Optimizing FDA’s Regulatory Oversight of Next Generation Sequencing Diagnostic Tests Public Workshop, February 20, 2015